São ___, Brazil Crossword Clue

 The answer to the crossword clue "São ___, Brazil" is Paulo. It is a 5-letter word.

São Paulo is the most populous city in Brazil and the largest city in the Southern Hemisphere. It is located in the southeastern part of the country, on the banks of the Tietê River. São Paulo is a major economic and cultural center, and is home to a number of universities, museums, and art galleries.

The name "São Paulo" comes from the Portuguese words "São" meaning "Saint" and "Paulo" meaning "Paul". The city was founded in 1554 by Jesuit missionaries, and was named after Saint Paul the Apostle.

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